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LIST OF PUBLICATIONS FEATURING CH TECHNOLOGIES PRODUCTS AND SYSTEMS 2007-PRESENT 


  • Se-Ran Yang , Jessica Wright , Mark Bauter , Kathryn Seweryniak , Aruna Kode , Irfan Rahman.  Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-κB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging. American Journal of Physiology - Lung Cellular and Molecular Physiology, February 2007,Vol. 292, no. L567-L576 (Cigarette smoke, JB2070) 

  • Marina Miller, Alexa Pham, Jae Youn Cho, Peter Rosenthal, and David H. Adiponectindeficient mice are protected against tobacco-induced inflammation and increased emphysema. Am J Physiol Lung Cell Mol Physiol. Dec 2010; 299(6): L834–L842. (Cigarette smoke, NOIES, CSM-SSM)  

  • Thomas H. Thatcher, Sanjay B. Maggirwar, Carolyn J. Baglole, Heather F. Lakatos, Thomas A. Gasiewicz, Richard P. Phipps, Patricia J. Sime. Aryl Hydrocarbon ReceptorDeficient Mice Develop Heightened Inflammatory Responses to Cigarette Smoke and Endotoxin Associated with Rapid Loss of the Nuclear Factor-κB Component RelB. The American Journal of Pathology, Volume 170, Issue 3, March 2007, Pages 855–864. (Cigarette smoke, JB2070) 

  • Maria C. Kjellssona, Laura E. Via, Anne Goh, Danielle Weiner, Kang Min Low, Steven Kern, Goonaseelan Pillai, Clifton E. Barry III and Véronique Dartois. Pharmacokinetic Evaluation of the Penetration of Antituberculosis Agents in Rabbit Pulmonary Lesions. Antimicrob. Agents Chemother. January 2012 vol. 56 no. 1 446-45. (NOIES, BANG) 

  • Se-Ran Yang, Samantha Valvo, Hongwei Yao, Aruna Kode, Saravanan Rajendrasozhan, Indika Edirisinghe, Samuel Caito, David Adenuga, Ryan Henry, George Fromm, Sanjay Maggirwar, Jian-Dong Li, Michael Bulger, and Irfan Rahman. IKKα Causes Chromatin Modification on Pro-Inflammatory Genes by Cigarette Smoke in Mouse Lung. Am J Respir Cell Mol Biol. Jun 2008; 38(6): 689–698. (Cigarette smoke, JB2082) 

  • Crystal L. Loving, Mary Kennett, Gloria M. Lee, Vanessa K. Grippe and Tod J. Merkel. Murine Aerosol Challenge Model of Anthrax. Infect. Immun. June 2007 vol. 75 no. 6 2689-2698. (NOIES, Infectious agents) 

  • Saravanan Rajendrasozhan, Sangwoon Chung, Isaac K. Sundar, Hongwei Yao, and Irfan Rahman. Targeted disruption of NF-κB1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: a critical role of p50 in chromatin remodeling. American Journal of Physiology - Lung Cellular and Molecular Physiology, Feb 2010; 298(2): L197-L209. (Cigarette smoke, JB2070) 

  • Thomas H. Thatcher, Randi P. Benson, Richard P. Phipps, and Patricia J. Sime. High-dose but not low-dose mainstream cigarette smoke suppresses allergic airway inflammation by inhibiting T cell function. American Journal of Physiology - Lung Cellular and Molecular Physiology, Sep 2008; 295(3): L412-L421. (Cigarette smoke, JB2070) 

  • Eric R. Secor Jr, William F. Carson IV, Anurag Singh, Mellisa Pensa, Linda A. Guernsey, Craig M. Schramm, and Roger S. Thrall. Oral Bromelain Attenuates Inflammation in an Ovalbumin-Induced Murine Model of Asthma. Evidence-Based Complementary and Alternative Medicine, Volume 5 (2008), Issue 1, Pages 61-69. (BANG, NOIES) 

  • David Adenuga, Samuel Caito, Hongwei Yao, Isaac K. Sundar, Jae-Woong Hwang, Sangwoon Chung, Irfan Rahman. Nrf2 deficiency influences susceptibility to steroid resistance via HDAC2 reduction. Biochemical and Biophysical Research Communications, Volume 403, Issues 3–4, 17 December 2010, Pages 452–456. (Cigarette smoke, JB2070) 

  • Guoyan Cheng, Xiaomei Yuan, Matthew S. Tsai, Eckhard R. Podack, Aixin Yu and Thomas R. Malek. IL-2 Receptor Signaling Is Essential for the Development of Klrg1+ Terminally Differentiated T Regulatory Cells. The Journal of Immunology August 15, 2012 vol. 189 no. 4 1780-179. (BANG, NOIES, Infectious agents) 

  • Crystal L. Loving, Taruna Khurana, Manuel Osorio, Gloria M. Lee, Vanessa K. Kelly, Scott Stibitz and Tod J. Merkel. Role of Anthrax Toxins in Dissemination, Disease Progression, and Induction of Protective Adaptive Immunity in the Mouse Aerosol Challenge Model. Infect. Immun. January 2009 vol. 77 no. 1 255-265. (BANG, NOIES, Infectious agents) 

  • Saravanan Rajendrasozhan, Jae-Woong Hwang, Hongwei Yao, Nandini Kishore, Irfan Rahman.  Anti-inflammatory effect of a selective IκB kinase-beta inhibitor in rat lung in response to LPS and cigarette smoke. Pulmonary Pharmacology & Therapeutics, Volume 23, Issue 3, June 2010, Pages 172–181. (Cigarette smoke, JB2070) 

  • Heidi C. O'Neill, Carl W. White, Livia A. Veress, Tara B. Hendry-Hofer, Joan E. Loader, Elysia Min, Jie Huang, Raymond C. Rancourt, Brian J. Day. Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of the sulfur mustard analog 2-chloroethyl ethyl sulfide. Free Radical Biology and Medicine, Volume 48, Issue 9, 1 May 2010, Pages 1188–1196. (Collison nebulizer, NOIES) 

  • Daniel F. Catanzaro, Ying Zhou, Rong Chen, Fangmin Yu, Sarah E. Catanzaro, Mariana S. De Lorenzo, Kotha Subbaramaiah, Xi Kathy Zhou, Domenico Pratico, Andrew J. Dannenberg, Babette B. Weksler. Potentially Reduced Exposure Cigarettes Accelerate Atherosclerosis: Evidence for the Role of Nicotine. Cardiovascular Toxicology, September 2007, Volume 7, Issue 3, pp 192-201. (Cigarette smoke, NOIES, CSM-SSM) 

  • Gnanapragasam Arunachalam, Isaac K Sundar, Jae-woong Hwang, Hongwei Yao and Irfan Rahman. Emphysema is associated with increased inflammation in lungs of atherosclerosisprone mice by cigarette smoke: implications in comorbidities of COPD. Journal of Inflammation 2010, 7:34  doi:10.1186/1476-9255-7-34. (Cigarette smoke, JB2070) 

  • Crystal L. Loving, Manuel Osorio, Yun-Gi Kim, Gabriel Nuñez, Molly A. Hughes and Tod J. Merkel. Nod1/Nod2-Mediated Recognition Plays a Critical Role in Induction of Adaptive Immunity to Anthrax after Aerosol Exposure. Infect. Immun., October 2009, vol. 77, no. 10, 4529-4537. (BANG, NOIES, Infectious agents) 

  • Christine Nadziejko, Kaije Fang, Antonio Bravo, and Terry Gordon. Susceptibility to pulmonary hypertension in inbred strains of mice exposed to cigarette smoke. Journal of Applied Physiology, May 2007, vol. 102, no. 5, 1780-1785. (Cigarette smoke, JB2070) 

  • Dae Jin Song, Myung Goo Min, [...], and David H. Broide. Environmental tobacco smoke exposure does not prevent corticosteroids reducing inflammation, remodeling, and airway hyperreactivity in mice exposed to allergen. American Journal of Physiology - Lung Cellular and Molecular Physiology, Aug 2009; 297(2): L380-L387. (Cigarette smoke, CSM-SSM) 

  • Song D.J., Min M.G., Miller M., Cho J.Y., Yum H.Y., Broide D.H. Toll-Like Receptor-9 Agonist Inhibits Airway Inflammation, Remodeling and Hyperreactivity in Mice Exposed to Chronic Environmental Tobacco Smoke and Allergen. Int Arch Allergy Immunol, Vol. 151: 286296, No. 4, 2010. (Cigarette smoke, CSM-SSM) 

  • William R. Kirkpatrick, Laura K. Najvar, Ana C. Vallor, Nathan P. Wiederhold, Rosie Bocanegra, Juergen Pfeiffer, Kimberly Perkins, Alan R. Kugler, Theresa D. Sweeney and Thomas F. Patterson. Prophylactic efficacy of single dose pulmonary administration of amphotericin B inhalation powder in a guinea pig model of invasive pulmonary aspergillosis. J. Antimicrob. Chemother. (2012), 67 (4): 970-976. (NOIES) 

  • Chuen-Chau Chang, Jing-Shiang Hwang, Chang-Chuan Chan, Peng-Yau Wang and TsunJen Cheng. Concentrated Ambient Particles on Heart Rate, Blood Pressure, and Cardiac Contractility in Spontaneously Hypertensive Rats During a Dust Storm Event. Inhalation Toxicology, 2007, Vol. 19, No. 11 , Pages 973-978. (NOIES) 

  • Chad J. Roy, Satheesh K. Sivasubramani, Noton K. Dutta, Smriti Mehra, Nadia A. Golden, Stephanie Killeen, James D. Talton, Badre E. Hammoud, Peter J. Didier and Deepak Kaushal. Aerosolized Gentamicin Reduces the Burden of Tuberculosis in a Murine Model. Antimicrob. Agents Chemother. February 2012, vol. 56, no. 2:883-886. (BANG, NOIES, Infectious agents) 

  • Se-Ran Yang, Hongwei Yao, Saravanan Rajendrasozhan, Sangwoon Chung, Indika Edirisinghe, Samantha Valvo, George Fromm, Michael J. McCabe, Jr., Patricia J. Sime, Richard P. Phipps, Jian-Dong Li, Michael Bulger and Irfan Rahman. RelB Is Differentially Regulated by IκB Kinase-α in B Cells and Mouse Lung by Cigarette Smoke. Am J Respir Cell Mol Biol, Feb 2009, 40(2):147-158. (Cigarette smoke, JB2070) 

  • Richard W. Chapman, Aileen House, Howard Jones, Jennifer Richard, Chander Celly, Dan Prelusky, Pauline Ting, John C. Hunter, James Lamca, Jonathan E. Phillips. Effect of inhaled roflumilast on the prevention and resolution of allergen-induced late phase airflow obstruction 

  • in Brown Norway rats. European Journal of Pharmacology, Volume 571, Issues 2–3, 1 October 2007, Pages 215–221. (Rat restraint tubes) 

  • Nicole N. Driessen, Helena I. M. Boshoff, Janneke J. Maaskant, Sebastiaan A. C. Gilissen, Simone Vink, Astrid M. van der Sar, Christina M. J. E. Vandenbroucke-Grauls, Carole A. Bewley, Ben J. Appelmelk and Jeroen Geurtsen. Cyanovirin-N Inhibits Mannose-Dependent Mycobacterium–C-Type Lectin Interactions but Does Not Protect against Murine Tuberculosis. The Journal of Immunology October 1, 2012 vol. 189 no. 7 3585-3592. (BANG, NOIES) 

  • Lida Mohtasham, Alexander Auais and Giovanni Piedimonte. Nerve growth factor mediates steroid-resistant inflammation in respiratory syncytial virus infection. Pediatric Pulmonology, Volume 42, Issue 6, pages 496–504, June 2007. (NOIES) 

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  • D. Saini, R. M. Buller, A. S. Biris and P. Biswas. Characterization of a Nose-Only Inhalation Exposure System for Ectromelia Virus Infection of Mice. Particulate Science and Technology: An International Journal, Volume 27, Issue 2, 2009, p.152-165. (BANG, NOIES) 

  • Matthew J. Panzner, Khadijah M. Hindi, Brian D. Wright, Jane B. Taylor, Daniel S. Han, Wiley J. Youngs and Carolyn L. Cannon. A theobromine derived silver N-heterocyclic carbene: synthesis, characterization, and antimicrobial efficacy studies on cystic fibrosis relevant pathogens. Dalton Transactions, Issue 35: 7308-7313, 2009. (NOIES) 

  • Fernando M. Botelho, Gordon J. Gaschler, Sussan Kianpour, Cale C. J. Zavitz, Nancy J. Trimble, Jake K. Nikota, Carla M. T. Bauer, and Martin R. Stämpfli. Innate Immune Processes Are Sufficient for Driving Cigarette Smoke–Induced Inflammation in Mice. American Journal of Respiratory Cell and Molecular Biology, Vol. 42, No. 4 (2010), pp. 394-403. (Cigarette Smoke) 

  • Anurag Singh, Roger S Thrall, Linda A Guernsey, William F Carson IV, Eric R Secor Jr, Robert E Cone, Thiruchandurai V Rajan and Craig M Schramm. Subcutaneous late phase responses are augmented during local inhalational tolerance in a murine asthma model. Immunology and Cell Biology (2008) 86, 535–538, May 2008. (BANG, NOIES) 

  • Amy L. Hartman, Diana S. Powell, Laura M. Bethel, Amy L. Caroline, Richard J. Schmid, Tim Oury and Douglas S. Reed. Aerosolized Rift Valley Fever Virus Causes Fatal Encephalitis in African Green Monkeys and Common Marmosets. J. Virol. February 2014 vol. 88 no. 4 22352245. (BANG, NOIES) 

  • Kexiong Lin, Shuanglin Liu, Yibo Shen, Qi Li. Berberine Attenuates Cigarette SmokeInduced Acute Lung Inflammation. Inflammation, October 2013, Volume 36, Issue 5, pp 10791086. (Cigarette Smoke, WBE) 

  • Raymond C. Rancourt, Livia A. Veress, Aftab Ahmad, Tara B. Hendry-Hofer, Jacqueline S. Rioux, Rhonda B. Garlick, Carl W. White. Tissue factor pathway inhibitor prevents airway 

  • obstruction, respiratory failure and death due to sulfur mustard analog inhalation. Toxicology and Applied Pharmacology, Volume 272, Issue 1, 1 October 2013, Pages 86–95. (NOIES) 

  • Sangwoon Chung, Isaac K. Sundar, Jae-Woong Hwang, Fiona E. Yull, Timothy S. Blackwell, Vuokko L. Kinnula, Michael Bulger, Hongwei Yao, Irfan Rahman. NF-κB Inducing Kinase, NIK Mediates Cigarette Smoke/TNFα-Induced Histone Acetylation and Inflammation through Differential Activation of IKKs. PLoS ONE 6(8): e23488. doi:10.1371/journal.pone.0023488. (Cigarette Smoke, JB 2070) 

  • Hongwei Yao, Indika Edirisinghe, Se-Ran Yang, Saravanan Rajendrasozhan, Aruna Kode, Samuel Caito, David Adenuga, Irfan Rahman. Genetic Ablation of NADPH Oxidase Enhances Susceptibility to Cigarette Smoke-Induced Lung Inflammation and Emphysema in Mice. The American Journal of Pathology, Volume 172, Issue 5, May 2008, Pages 1222–1237. (Cigarette Smoke, JB 2070) 

  • Yanjun Wu, Charles J. Kotzer, Sokratis Makrogiannis, Gregory A. Logan, Hyking Haley, Mary S. Barnette, Susanta K. Sarkar. A Noninvasive [99mTc]DTPA SPECT/CT Imaging Methodology as a Measure of Lung Permeability in a Guinea Pig Model of COPD. Molecular Imaging and Biology, October 2011, Volume 13, Issue 5, pp 923-929. (Cigarette Smoke, JB 2070, NOIES) 

  • John T. Bernert, Sydney M. Gordon, Ram B. Jain, Marielle C. Brinkman, Connie S. Sosnoff, Tiffany H. Seyler, Yang Xia, James E. McGuffey, David L. Ashley, James L. Pirkle, Eric J. Sampson. Increases in tobacco exposure biomarkers measured in non-smokers exposed to sidestream cigarette smoke under controlled conditions. Biomarkers, March 2009, Vol. 14, No. 2, Pages 82-93. (Cigarette Smoke, JB 2070) 

  • Hongwei Yao, Jae-woong Hwang, Jorge Moscat, Maria T. Diaz-Meco, Michael Leitges, Nandini Kishore, Xiong Li and Irfan Rahman. Protein Kinase Cζ Mediates Cigarette Smoke/Aldehyde- and Lipopolysaccharide-induced Lung Inflammation and Histone Modifications. The Journal of Biological Chemistry, 2010, 285, 5405-5416. (Cigarette Smoke, JB 2070) 

  • Susan T. Gater, Kristen N. Peters, Andrew G. Kocsis, Miqdad O. Dhariwala, Deborah M. Anderson, and Paul E. Anderson. Host stress and immune responses during aerosol challenge of Brown Norway rats with Yersinia pestis. Front Cell Infect Microbiol. 2012; 2: 147. (SLAG, NOIES) 

  • Shanshan Cai, Rachel L. Zemans, Scott K. Young, G. Scott Worthen, and Samithamby Jeyaseelan. Myeloid Differentiation Protein-2–Dependent and –Independent Neutrophil Accumulation during Escherichia coli Pneumonia. Am J Respir Cell Mol Biol. Jun 2009; 40(6): 701–709. (BANG, NOIES) 

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  • P. Meers, M. Neville, V. Malinin, A. W. Scotto, G. Sardaryan, R. Kurumunda, C. Mackinson, G. James, S. Fisher and W. R. Perkins. Biofilm penetration, triggered release and in vivo activity of inhaled liposomal amikacin in chronic Pseudomonas aeruginosa lung infections. J. Antimicrob. Chemother. (2008) 61 (4): 859-868. (NOIES) 

  • Adam P Matson, Roger S Thrall, Ektor Rafti, Elizabeth G Lingenheld and Lynn Puddington. IgG transmitted from allergic mothers decreases allergic sensitization in breastfed offspring. Clinical and Molecular Allergy, 2010, 8:9. (BANG) 

  • Khadijah M. Hindia, Andrew J. Dittob, Matthew J. Panznera, Douglas A. Medvetza, Daniel S. Hanc, Christine E. Hovisc, Julia K. Hilliardc, Jane B. Taylorc, Yang H. Yunb, Carolyn L. Cannonc, Wiley J. Youngsa. The antimicrobial efficacy of sustained release silver–carbene complex-loaded l-tyrosine polyphosphate nanoparticles: Characterization, in vitro and in vivo studies. Biomaterials, Volume 30, Issue 22, August 2009, Pages 3771–3779. (NOIES) 

  • Patricia L. Podolin , Joseph P. Foley , Donald C. Carpenter , Brian J. Bolognese , Gregory A. Logan , Edward Long III, Oliver J. Harrison , Patrick T. Walsh. T cell depletion protects against alveolar destruction due to chronic cigarette smoke exposure in mice. American Journal of Physiology - Lung Cellular and Molecular Physiology, March 2013, Vol. 304 no. L312-L323. (Cigarette Smoke, JB2070) 

  • Eric R. Secor Jr., Sonali J. Shah, Linda A. Guernsey, Craig M. Schramm, Roger S. Thrall. Bromelain Limits Airway Inflammation in an Ovalbumin-induced Murine Model of Established Asthma. Alternative Therapies in Health & Medicine . Sep/Oct2012, Vol. 18 Issue 5, p9-17. 9p. (BANG, NOIES) 

  • Hongwei Yao, Se-Ran Yang, Indika Edirisinghe, Saravanan Rajendrasozhan, Samuel Caito, David Adenuga, Michael A. O'Reilly, and Irfan Rahman. Disruption of p21 Attenuates Lung Inflammation Induced by Cigarette Smoke, LPS, and fMLP in Mice. Am J Respir Cell Mol Biol. Jul 2008; 39(1): 7–18. (Cigarette Smoke, JB2070) 

  • Thomas H. Thatcher , Hsi-Min Hsiao , Elhanan Pinner , Moshe Laudon , Stephen J. Pollock , Patricia J. Sime , Richard P. Phipps. Neu-164 and Neu-107, two novel antioxidant and anti-myeloperoxidase compounds, inhibit acute cigarette smoke-induced lung inflammation. American Journal of Physiology - Lung Cellular and Molecular PhysiologyPublished 15 July 2013Vol. 305no. L165-L174. (Cigarette Smoke, JB2070) 

  • Seth A.Faith, Le'Kneitah P. Smith, Angela S. Swatland, Douglas S. Reed. Growth conditions and environmental factors impact aerosolization but not virulence of Francisella tularensis infection in mice. Frontiers in Cellular & Infection Microbiology . Sep 2012, Vol. 2, p2-36. 35p. (NOIES) 

  • Michelle Natiello, George Kelly, James Lamca, David Zelmanovic, Richard W. Chapman, Jonathan E. Phillips. Manual and automated leukocyte differentiation in bronchoalveolar lavage 

  • fluids from rodent models of pulmonary inflammation. Comparative Clinical Pathology, May 2009, Volume 18, Issue 2, pp 101-111. (Cigarette Smoke, JB2070) 

  • Laurence D. Fechter, Caroline A. Gearhart and Sherry Fulton. Ototoxic Potential of JP-8 and a Fischer-Tropsch Synthetic Jet Fuel following Subacute Inhalation Exposure in Rats. Toxicol. Sci. (2010) 116 (1): 239-248. (NOIES) 

  • Jorrit J Hofstra, Alexander D Cornet, Bart F de Rooy, Alexander P Vlaar, Tom van der Poll, Marcel Levi, Sebastian AJ Zaat and Marcus J Schultz. Nebulized antithrombin limits bacterial outgrowth and lung injury in Streptococcus pneumonia pneumonia in rats. Critical Care, 2009, 13:R145. (NOIES) 

  • Carol A. Wu, John J. Peluso, Li Zhu, Elizabeth G. Lingenheld, Sharale T. Walker, Lynn Puddington. Bronchial epithelial cells produce IL-5: Implications for local immune responses in the airways. Cellular Immunology, Volume 264, Issue 1, 2010, Pages 32–41. (BANG) 

  • Sheung P. Ng, Daniel J. Conklin, Aruni Bhatnagar, Duane D. Bolanowski, Jessica Lyon, and Judith T. Zelikoff. Prenatal Exposure to Cigarette Smoke Induces Diet- and Sex-Dependent Dyslipidemia and Weight Gain in Adult Murine Offspring. Environ Health Perspect. Jul 2009; 117(7): 1042–1048. (Cigarette Smoke, JB2070) 

  • S. Paveglio, L. Puddington, E. Rafti and A. P. Matson. FcRn-mediated intestinal absorption of IgG anti-IgE/IgE immune complexes in mice. Clinical & Experimental Allergy, Volume 42, Issue 12, pages 1791–1800, December 2012. (BANG, NOIES) 

  • Lynn P. Webera, Ahmad Al-Dissia, Jordan S. Marit, Timothy N. German, Sharilyn D. Terletski. Role of carbon monoxide in impaired endothelial function mediated by acute secondhand tobacco, incense, and candle smoke exposures. Environmental Toxicology and Pharmacology, Volume 31, Issue 3, May 2011, Pages 453–459. (Cigarette Smoke, CSM-SCM) 

  • Zhu Li, Gayathri Chadalapaka, Aramandla Ramesh, Habibeh Khoshbouei, Mark Maguire, Stephen Safe, Raina E. Rhoades, Ryan Clark, George Jules, Monique McCallister, Michael Aschner and Darryl B. Hood. PAH Particles Perturb Prenatal Processes and Phenotypes: Protection from Deficits in Object Discrimination Afforded by Dampening of Brain Oxidoreductase Following In Utero Exposure to Inhaled Benzo(a)pyrene. Toxicol. Sci. (2012) 125 (1): 233-247. (NOIES, RBG) 

  • Isaac K. Sundar, Sangwoon Chung, Jae-woong Hwang, John D. Lapek Jr., Michael Bulger, Alan E. Friedman, Hongwei Yao, James R. Davie and Irfan Rahman. Mitogen- and StressActivated Kinase 1 (MSK1) Regulates Cigarette Smoke-Induced Histone Modifications on NFκB-dependent Genes. PLoS ONE 7(2): e31378. doi:10.1371/journal.pone.0031378. (Cigarette Smoke, JB2070) 

  • Carol A. Wu, John J. Peluso, John D. Shanley, Lynn Puddington, Roger S. Thrall. Murine Cytomegalovirus Influences Foxj1 Expression, Ciliogenesis, and Mucus Plugging in Mice with Allergic Airway Disease. The American Journal of Pathology, Volume 172, Issue 3, March 2008, Pages 714–724. (BANG, NOIES) 

  • Robert Fountaine, Ashley Milton, Tina Checchio, Greg Wei, Marilyn Stolar, John Teeter, Rudolph Jaeger and David Fryburg. Acute passive cigarette smoke exposure and inhaled human insulin (Exubera®) pharmacokinetics. British Journal of Clinical Pharmacology, Volume 65, Issue 6, pages 864–870, June 2008. (Cigarette Smoke, JB2070) 

  • Zhenqiang Xua, Yan Wua, Fangxia Shena, Qi Chena, Miaomiao Tana & Maosheng Yaoa. Bioaerosol Science, Technology, and Engineering: Past, Present, and Future. Aerosol Science and Technology, Volume 45, Issue 11, 2011. (SLAG) 

  • Nicole J. Gentner, Lynn P. Weber. Using blood pressure telemetry to assess acute changes in arterial stiffness in rats after nitric oxide synthase inhibition or environmental tobacco smoke exposure. Canadian Journal of Physiology and Pharmacology, 2010, 88(9): 918-928. (Cigarette Smoke, CSM-SCM) 

  • Edward L. Carmines and Narayanan Rajendran. Evidence for Carbon Monoxide as the Major Factor Contributing to Lower Fetal Weights in Rats Exposed to Cigarette Smoke. Toxicol. Sci. (2008) 102 (2): 383-391. (Cigarette Smoke, NOIES) 

  • Jenny Rissler, Lars Asking, and Jakob Kisbye Dreyer. A Methodology to Study Impactor Particle Reentrainment and a Proposed Stage Coating for the NGI. Journal of Aerosol Medicine and Pulmonary Drug Delivery. December 2009, 22(4): 309-316. (Vilnius Aerosol Generator) 

  • Indika Edirisinghe, Se-Ran Yang, Hongwei Yao, Saravanan Rajendrasozhan, Samuel Caito, David Adenuga, Chelsea Wong, Arshad Rahman, Richard P. Phipps, Zheng-Gen Jin and Irfan Rahman. VEGFR-2 inhibition augments cigarette smoke-induced oxidative stress and inflammatory responses leading to endothelial dysfunction. The FASEB Journal, July 2008, vol. 22, no. 7:2297-2310. (Cigarette Smoke, JB2070) 

  • Paula J. Brunton, Matthias Sausbier, Georg Wietzorrek, Ulrike Sausbier, Hans-Guenther Knaus, John A. Russell, Peter Ruth, and Michael J. Shipston. Hypothalamic-Pituitary-Adrenal Axis Hyporesponsiveness to Restraint Stress in Mice Deficient for Large-Conductance Calcium- and Voltage-Activated Potassium (BK) Channels. Endocrinology, Volume 148 Issue 11 | November 1, 2007. (Rat restraint tubes) 

  • Dennis M. Klinman, Debra Currie, Gloria Lee, Vanessa Grippe and Tod Merkel. Systemic but not mucosal immunity induced by AVA prevents inhalational anthrax. Microbes and Infection, Volume 9, Issues 12–13, October 2007, Pages 1478–1483. (Collison nebulizer, NOIES, Infectious agents) 

  • Silvia S. Barbieri and Babette B. Weksler. Tobacco smoke cooperates with interleukin-1β to alter β-catenin trafficking in vascular endothelium resulting in increased permeability and induction of cyclooxygenase-2 expression in vitro and in vivo. The FASEB Journal, June 2007, vol. 21, no. 8:1831-1843. (Cigarette smoke, NOIES, CSM-SSM) 

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  • Impact of heterozygote CFTR Mutations in COPD patients withe Chronic Bronchitis

    Raju et al. Respiratory Research 2014, 15:18 http://respiratory-research.com/content/15/1/18

  • Identification of differentially expressed proteins in blood plasma of control and cigarette smoke-exposed mice by 2D differential in-gel electrophoresis/MS

    Published in final edited form as: Proteomics. 2011 May ; 11(10): 2051–2062. doi:10.1002/pmic.201000159.

  • Superiority of PC-SOD to other anti-COPD drugs for elastase-induced emphysema and alteration in lung mechanics and respiratory function in mice

    Am J Physiol Lung Cell Mol Physiol 302: L1250–L1261, 2012. First published April 13, 2012; doi:10.1152/ajplung.00019.201

  • Chronic Alcohol Induces M2 Polarization Enhancing Pulmonary Disease Caused by Exposure to Particulate Air Pollution

    ALCOHOLISM:CLINICAL AND EXPERIMENTAL RESEARCH Vol. 37, No. 11 November 2013

  • Breast milk–mediated transfer of an antigen induces tolerance and protection from allergic asthma

    ©2008 Nature Publishing Group  http://www.nature.com/naturemedicine

  • The oral administration of bacterial extracts prevents asthma via the recruitment of regulatory T cells to the

    nature publishing group ARTICLES airways

  • CX3CR1 is required for airway inflammation by promoting T helper cell survival and maintenance  in inflamed lung

    nature medicine  VOLUME 16 | NUMBER 11 | NOVEMBER 2010

  • Augmentation of arginase 1 expression by exposure to air pollution exacerbates the airways hyperresponsiveness in murine models of asthma 

    North et al. Respiratory Research 2011, 12:19 http://respiratory-research.com/content/12/1/19

  • Superiority of PC-SOD to other anti-COPD drugs for elastase-induced emphysema and alteration in lung mechanics and respiratory function in mice

    Am J Physiol Lung Cell Mol Physiol 302: L1250–L1261, 2012. First published April 13, 2012; doi:10.1152/ajplung.00019.2012.

  • Dose-dependent effects of endotoxins on allergen sensitization and challenge in the mous

    Clin Exp Allergy 2004; 34:1789–1795 doi:10.1111/j.1365-2222.2004.02082.x

      ......

IQ,安装确认(Installation Qualification),确认仪器文件、部件及安装过程。 

OQ,运行确认(Operational Qualification),确认仪器在空转状态下,在操作的极限范围内能作正常的运转。

PQ,性能确认(Performance Qualification),确认仪器载样运行下是否符合标准规定。



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